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HyalOne 60 mg Injection is used to treat pain in osteoarthritis patients who have not received adequate relief from simple pain medications or exercise and physical therapy. In adults over the age of 21, it is also used in plastic surgery to reduce wrinkles or folds on the face and to enhance the lips. HyalOne is a sterile, non-pyrogenic, and highly elastic injectable solution, which is based on purified sodium hyaluronate produced by bacterial fermentation of a high-molecular-weight fraction of hyaluronic acid. Hyaluronic acid is a substance naturally occurring in many tissues of the body, including cartilage and synovial fluid. It is a principal component of synovial fluid responsible for its viscosity and elasticity. Being a natural lubricant and shock absorber, hyaluronan is indispensable for proper joint function.